Mangosteen (Botanical name – Garcinia mangostana), also known as the purple mangosteen, is a tropical evergreen tree with edible fruit native to island nations of Southeast Asia. Mangosteen grows mainly in Southeast Asia, southwest India and other tropical areas such as Colombia, Puerto Rico and Florida, where the tree has been introduced. The tree grows from 6 to 25 m. The fruit of the mangosteen is sweet and tangy, juicy, somewhat fibrous, with fluid-filled vesicles (like the flesh of citrus fruits), with an inedible, deep reddish-purple colored rind (exocarp). Mangosteen is known for its traditional usage of a healing nature. Being a commercial fruit, Mangosteen has a significant demand from consumers due to its innocuous behavior and the ability to be consumed orally whether as a preventative dietary strategy or as a treatment plan. Scientific study of Mangosteen has confirmed presence of natural compounds such as xanthones (mangostin) and benzophenones are advantageous as drug candidates for inflammatory diseases pertaining to the nervous system, arthritis, cancer, and the digestive system as well as dermal and muscular issues. Mangosteen extract supports as anti-oxidant agent and helps to protect gastro-intestinal lining, improving its function. In recent years, the mangosteen has become a popular dietary supplement for its potential health promoting properties and in promoting weight loss. The mangosteen fruit is unique in that it is the most abundant source of a diverse “natural” chemical library of xanthones (Mangostin) and is largely responsible for their health promoting properties.